Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | TACR2 | P21452 | 12/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474454 | 0.91 | LMNA (0.53) | LMNAMAPTPKMTACR2KMT2A | |
| SCHEMBL8476333 | 0.91 | KDM4E (0.49) | LMNAMAPTTACR2KMT2APOLB | |
| SCHEMBL8472581 | 0.90 | KDM4E (0.46) | LMNATACR2KMT2APOLBKDM4E | |
| SCHEMBL8476916 | 0.90 | KDM4E (0.43) | LMNAMAPTKMT2AKDM4EALDH1A1 | |
| SCHEMBL8477583 | 0.89 | ALDH1A1 (0.46) | LMNAMAPTKMT2APOLBKDM4E | |
| SCHEMBL8476897 | 0.87 | ALDH1A1 (0.48) | LMNAKMT2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL8472561 | 0.87 | HDAC3 (0.41) | KMT2AEGFR | |
| SCHEMBL8472479 | 0.86 | SMN1; SMN2 (0.45) | LMNAKMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL8471992 | 0.86 | KMT2A (0.47) | LMNAMAPTPKMKMT2AKDM4E | |
| SCHEMBL8476854 | 0.85 | PTGER4 (0.42) | LMNAKMT2APOLBKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |