Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 7/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8550877 | 0.90 | CCR5 (0.51) | CCR5OPRK1SIGMAR1OPRM1TP53 | |
| SCHEMBL8551862 | 0.81 | TACR1 (0.41) | CCR5OPRK1OPRM1CYP2D6TACR1 | |
| SCHEMBL9098158 | 0.80 | CCR5 (0.49) | CCR5OPRK1SIGMAR1OPRM1TP53 | |
| SCHEMBL9097115 | 0.80 | CCR5 (0.48) | CCR5OPRK1SIGMAR1OPRM1TP53 | |
| SCHEMBL8553707 | 0.79 | CCR5 (0.48) | CCR5OPRK1OPRM1CYP2D6ALDH1A1 | |
| SCHEMBL9098644 | 0.79 | CCR5 (0.47) | CCR5OPRK1OPRM1TP53CYP3A4 | |
| SCHEMBL9097458 | 0.78 | CCR5 (0.47) | CCR5OPRK1SIGMAR1OPRM1TP53 | |
| SCHEMBL16333504 | 0.78 | TACR1 (0.46) | CCR5OPRK1SIGMAR1OPRM1TP53 | |
| SCHEMBL6982329 | 0.77 | OPRK1 (0.53) | CCR5OPRK1OPRM1TP53CYP3A4 | |
| SCHEMBL6982333 | 0.77 | OPRK1 (0.53) | CCR5OPRK1OPRM1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5952369-A | ANALGESIC, TREATMENT FOR STROKE OR ABDOMINAL PAIN ASSOCIATED WITH FUNCTIONAL BOWEL DISEASE | PFIZER INC (US) | 1999-09-14 | — | — | US | disclosed |