Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 2/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 10/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476568 | 0.90 | CCR5 (0.43) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8553707 | 0.89 | CCR5 (0.48) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL9098158 | 0.88 | CCR5 (0.49) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL9097115 | 0.87 | CCR5 (0.48) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8551862 | 0.86 | TACR1 (0.41) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8626578 | 0.86 | OPRD1 (0.57) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8547882 | 0.85 | CCR5 (0.43) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL9097458 | 0.85 | CCR5 (0.47) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8552457 | 0.85 | CCR5 (0.48) | CCR5OPRK1OPRM1OPRD1CYP2D6 | |
| SCHEMBL8551509 | 0.85 | SIGMAR1 (0.39) | CCR5OPRK1OPRM1OPRD1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | claimed |
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | disclosed |