Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR5 | P51681 | 3/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 9/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.39 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.39 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.39 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8552457 | 0.90 | CCR5 (0.48) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8550877 | 0.89 | CCR5 (0.51) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8551509 | 0.88 | SIGMAR1 (0.39) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8547882 | 0.86 | CCR5 (0.43) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8551862 | 0.85 | TACR1 (0.41) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8552270 | 0.84 | SLC6A2 (0.43) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8476568 | 0.79 | CCR5 (0.43) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL9098158 | 0.77 | CCR5 (0.49) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8922022 | 0.76 | CCR5 (0.54) | CCR5OPRM1OPRD1OPRK1CYP2D6 | |
| SCHEMBL8670577 | 0.76 | CCR5 (0.54) | CCR5OPRM1OPRD1OPRK1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0817772-A1 | PYRROLIDINYL HYDROXAMIC ACID COMPOUNDS AND THEIR PRODUCTION PROCESS | PFIZER INC. (US) | 1998-01-14 | — | — | EP | claimed |