Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.34 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474416 | 0.82 | TAAR1 (0.32) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8475300 | 0.82 | LMNA (0.37) | SMN1; SMN2KIF11ALDH1A1LMNAMAPK1 | |
| SCHEMBL8477680 | 0.80 | SMN1; SMN2 (0.40) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL28114102 | 0.79 | MEN1 (0.44) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8474278 | 0.78 | MEN1 (0.41) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8477930 | 0.77 | CYP19A1 (0.40) | MEN1KMT2ALMNAHTTNPSR1 | |
| SCHEMBL8477408 | 0.72 | CYP2C9 (0.51) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL8476961 | 0.71 | SLC6A2 (0.35) | SMN1; SMN2KCNA5NPSR1HTR2AKCNH2 | |
| SCHEMBL7453249 | 0.70 | CALM1 (0.41) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 | |
| SCHEMBL2019079 | 0.70 | MEN1 (0.40) | MEN1KMT2ACYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |