Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
| ▸ | HNF4A | P41235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473979 | 0.84 | DHFR (0.34) | ALDH1A1HPGDHSD17B10MAPT | |
| SCHEMBL8474671 | 0.83 | BACE1 (0.33) | BACE1 | |
| SCHEMBL15550742 | 0.80 | DHFR (0.43) | — | |
| SCHEMBL8477966 | 0.80 | DHFR (0.38) | BACE1LMNAMAPTHTTPDCD1 | |
| SCHEMBL8480981 | 0.79 | PTGS2 (0.46) | BACE1HDAC4HDAC2HDAC8 | |
| SCHEMBL1403616 | 0.79 | ACMSD (0.41) | TDP1BACE1ALDH1A1MAPT | |
| SCHEMBL11040917 | 0.79 | CALM1 (0.38) | TDP1ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL4569916 | 0.75 | TDP1 (0.31) | TDP1 | |
| SCHEMBL8497176 | 0.73 | BACE1 (0.43) | BACE1ALDH1A1HPGDHSD17B10HDAC4 | |
| SCHEMBL7464716 | 0.71 | GCGR (0.38) | ALDH1A1HPGDLMNAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |