Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALM1 | P0DP23 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8859945 | 0.81 | CALM1 (0.37) | CALM1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8477966 | 0.80 | DHFR (0.38) | L3MBTL1LMNAMAPTHTT | |
| SCHEMBL8477404 | 0.79 | TDP1 (0.38) | HPGDALDH1A1TDP1LMNAMAPT | |
| SCHEMBL8473979 | 0.77 | DHFR (0.34) | TSHRRAB9ASMN1; SMN2NPC1HPGD | |
| SCHEMBL8466360 | 0.74 | CALM1 (0.55) | CALM1CYP3A4MAOBTSHRHPGD | |
| SCHEMBL15550742 | 0.73 | DHFR (0.43) | TSHR | |
| SCHEMBL891578 | 0.71 | LMNA (0.36) | MAOBHPGDALDH1A1LMNAMAPT | |
| SCHEMBL6250246 | 0.69 | LMNA (0.34) | HPGDALDH1A1LMNAMAPTHTT | |
| SCHEMBL8497176 | 0.69 | BACE1 (0.43) | PTPN1MEN1KMT2AHPGDALDH1A1 | |
| SCHEMBL522214 | 0.69 | HSD17B10 (0.41) | CYP3A4MEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002196-B1 | AMINE TERMINATED BLOCK COPOLYMERS AND PROCESSES FOR THEIR PREPARATION | THE FIRESTONE TIRE & RUBBER COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0032681-A2 | Hindered bis-phenol phenyl phosphites and synthetic resin compositions having enhanced stability to heat and light | ADEKA ARGUS CHEMICAL CO., Ltd. (JP) | 1981-07-29 | — | — | EP | disclosed |