Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4771853 | 0.85 | GAA (0.39) | GAASMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL11083920 | 0.85 | GAA (0.39) | GAASMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL15513489 | 0.83 | GAA (0.38) | GAASMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL9360259 | 0.83 | ALDH1A1 (0.48) | GAASMN1; SMN2ALDH1A1MAPTTSHR | |
| SCHEMBL28317409 | 0.82 | SIGMAR1 (0.50) | GAAALDH1A1MAPTMTNR1AMTNR1B | |
| SCHEMBL27380444 | 0.82 | GABRA1 (0.41) | GAASMN1; SMN2TSHRTSPOLMNA | |
| SCHEMBL27377820 | 0.79 | LMNA (0.41) | GAAALDH1A1MAPTTSPOLMNA | |
| SCHEMBL5167275 | 0.78 | NPSR1 (0.46) | SMN1; SMN2ALDH1A1TSHRTP53AKR1C3 | |
| SCHEMBL28245573 | 0.74 | ALOX5 (0.46) | GAAALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL21513960 | 0.74 | GAA (0.70) | GAASMN1; SMN2ALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9176127-B2 | Method for selecting a candidate drug compound | PEPSCAN SYSTEMS B.V. (NL) | 2015-11-03 | — | — | US | disclosed |
| US-20140308303-A1 | METHOD FOR SELECTING A CANDIDATE DRUG COMPOUND | PEPSCAN SYSTEMS B.V. (NL) | 2014-10-16 | — | — | US | disclosed |
| US-20140296478-A1 | METHOD FOR SELECTING A CANDIDATE DRUG COMPOUND | PEPSCAN SYSTEMS B.V. (NL) | 2014-10-02 | — | — | US | disclosed |
| EP-1844337-B1 | BINDING COMPOUNDS, IMMUNOGENIC COMPOUNDS AND PEPTIDOMIMETICS | PEPSCAN SYSTEMS BV (NL) | 2013-07-03 | — | — | EP | disclosed |
| EP-1597585-B1 | METHOD FOR SELECTING A CANDIDATE DRUG COMPOUND | PEPSCAN SYSTEMS BV (NL) | 2011-06-15 | — | — | EP | disclosed |
| US-20100322945-A1 | IMMUNOGENIC COMPOUNDS AND PROTEIN MIMICS | PEPSCAN SYSTEMS B.V. (NL) | 2010-12-23 | — | — | US | disclosed |
| EP-2052253-A2 | IMMUNOGENIC COMPOUNDS AND PROTEIN MIMICS | PEPSCAN SYSTEMS B.V. (NL) | 2009-04-29 | — | — | EP | disclosed |
| US-20080313749-A1 | Binding Compounds, Immunogenic Compounds and Peptidomimetics | PEPSCAN SYSTEMS B.V. (NL) | 2008-12-18 | — | — | US | disclosed |
| WO-2008013454-A2 | IMMUNOGENIC COMPOUNDS AND PROTEIN MIMICS | PEPSCAN SYSTEMS B.V. (NL) | 2008-01-31 | — | — | WO | disclosed |
| EP-1844337-A1 | BINDING COMPOUNDS, IMMUNOGENIC COMPOUNDS AND PEPTIDOMIMETICS | PEPSCAN SYSTEMS B.V. (NL) | 2007-10-17 | — | — | EP | disclosed |
| WO-2006078161-A1 | BINDING COMPOUNDS, IMMUNOGENIC COMPOUNDS AND PEPTIDOMIMETICS | PEPSCAN SYSTEMS B.V. (NL) | 2006-07-27 | — | — | WO | disclosed |
| EP-1597585-A2 | METHOD FOR SELECTING A CANDIDATE DRUG COMPOUND | PEPSCAN SYSTEMS B.V. (NL) | 2005-11-23 | — | — | EP | disclosed |
| WO-2004077062-A2 | METHOD FOR SELECTING A CANDIDATE DRUG COMPOUND | PEPSCAN SYSTEMS B.V. (NL) | 2004-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080313749-A1 | Binding Compounds, Immunogenic Compounds and Peptidomimetics | CXCL10, CCL2, CD74 | GAA 3192/4885SMN1; SMN2 4730/4885ALDH1A1 4812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.