Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.41 |
| ▸ | FABP3 | P05413 | 2/20 | 0.40 |
| ▸ | FABP4 | P15090 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479733 | 0.77 | ALDH1A1 (0.45) | FABP4RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL8483746 | 0.77 | ALDH1A1 (0.46) | PBRM1FABP3FABP4RAB9ASMN1; SMN2 | |
| SCHEMBL8479136 | 0.74 | GAA (0.42) | PBRM1FABP3FABP4ALDH1A1GAA | |
| SCHEMBL9094525 | 0.73 | KDM4E (0.46) | RAB9ASMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL9094581 | 0.73 | GRIK1 (0.48) | RAB9ASMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL11157305 | 0.73 | ALDH1A1 (0.47) | PBRM1FABP3FABP4SMN1; SMN2ALDH1A1 | |
| SCHEMBL744075 | 0.71 | RAB9A (0.65) | RAB9ASMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8485493 | 0.70 | ALDH1A1 (0.44) | RAB9ASMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL8855171 | 0.69 | HTT (0.45) | RAB9ASMN1; SMN2ALDH1A1GAAKDM4E | |
| SCHEMBL8479485 | 0.69 | ALDH1A1 (0.49) | RAB9AALDH1A1GAAKDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010015-A1 | CRYPTOLEPINE ANALOGS WITH HYPOGLYCEMIC ACTIVITY | SHAMAN PHARMACEUTICALS, INC. (US) | 1996-04-04 | — | — | WO | disclosed |