Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.44 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485288 | 0.99 | GAA (0.51) | GAASLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL8485004 | 0.93 | GAA (0.53) | GAASLC6A4OPRM1OPRD1OPRK1 | |
| SCHEMBL434932 | 0.92 | GAA (0.48) | GAASLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL1807144 | 0.86 | HSD11B1 (0.54) | GAASLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL9181522 | 0.85 | GAA (0.62) | GAASLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL3545231 | 0.82 | GAA (0.38) | GAASLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL31650310 | 0.81 | P2RX7 (0.46) | GAASMN1; SMN2LMNAKMT2ANPSR1 | |
| SCHEMBL1805474 | 0.81 | KAT2B (0.36) | GAASLC6A4SLC6A2SLC6A3OPRM1 | |
| SCHEMBL435377 | 0.80 | SLC6A3 (0.51) | SLC6A4SLC6A2SLC6A3KMT2AALDH1A1 | |
| SCHEMBL6803691 | 0.80 | LMNA (0.44) | GAAOPRM1SMN1; SMN2LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999015524-A1 | THIAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |