Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 8/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 7/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8857258 | 0.89 | KDM4E (0.40) | KMT2AMEN1ALDH1A1ADRB1ADRB3 | |
| SCHEMBL8857435 | 0.89 | HPGD (0.41) | KMT2AMEN1ALDH1A1CYP2D6 | |
| SCHEMBL8484201 | 0.79 | SIGMAR1 (0.45) | — | |
| SCHEMBL8974677 | 0.77 | PPARG (0.57) | KMT2AMEN1ALDH1A1ADRB1ADRB3 | |
| SCHEMBL8857706 | 0.75 | KMT2A (0.52) | KMT2AMEN1ALDH1A1ADRB1ADRB3 | |
| SCHEMBL8974734 | 0.72 | FFAR1 (0.56) | ADRB1ADRB3ADRB2 | |
| SCHEMBL8857607 | 0.72 | GRM2 (0.43) | — | |
| SCHEMBL8486948 | 0.72 | MAPT (0.44) | CYP2D6 | |
| SCHEMBL6032172 | 0.71 | MAPT (0.53) | KMT2AALDH1A1CYP2D6 | |
| SCHEMBL8974649 | 0.71 | FFAR1 (0.53) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688823-A | ANTILIPEMIC AGENTS, ANTIGLYCEMIC AGENTS, OBESITY, GLUCOSE TOLERANCE INSUFFICIENCY, INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1997-11-18 | — | — | US | disclosed |