Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAD52 | P43351 | 1/20 | 0.44 |
| ▸ | UBE2N | P61088 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | MAT2A | P31153 | 1/20 | 0.42 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.42 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.42 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.42 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.42 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.42 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8488740 | 0.79 | MAT2A (0.47) | ALDH1A1HPGDMAT2ALMNA | |
| SCHEMBL10487968 | 0.78 | ALDH1A1 (0.52) | USP2ALDH1A1HPGDTDP1LMNA | |
| SCHEMBL8046411 | 0.76 | MAT2A (0.52) | MAT2A | |
| SCHEMBL7026263 | 0.75 | ALDH1A1 (0.48) | MEN1KMT2AUSP2ALDH1A1TDP1 | |
| SCHEMBL10488012 | 0.72 | APOBEC3A (0.51) | MEN1KMT2AUSP2POLBALDH1A1 | |
| SCHEMBL7309368 | 0.69 | MAT2A (0.44) | ALDH1A1HPGDMAT2A | |
| SCHEMBL28811538 | 0.69 | TK1 (0.56) | MEN1KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL28811576 | 0.69 | TK1 (0.56) | MEN1KMT2AALDH1A1TDP1LMNA | |
| SCHEMBL10487991 | 0.68 | ALDH1A1 (0.46) | MEN1KMT2AUSP2POLBALDH1A1 | |
| SCHEMBL11999972 | 0.68 | KDM4E (0.56) | MEN1KMT2AUSP2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6001831-A | Process for producing quinazoline derivatives | CLARIANT GMBH (DE) | 1999-12-14 | — | — | US | disclosed |