Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668077 | 0.95 | OPRK1 (0.32) | OPRK1HTR1ADRD2 | |
| SCHEMBL8503795 | 0.91 | OPRK1 (0.31) | OPRK1 | |
| SCHEMBL8485150 | 0.88 | L3MBTL1 (0.41) | OPRK1DRD2 | |
| SCHEMBL8485599 | 0.84 | MTR (0.38) | — | |
| SCHEMBL8479247 | 0.80 | SCN1A (0.37) | — | |
| SCHEMBL8480413 | 0.80 | TMEM97 (0.35) | OPRK1 | |
| SCHEMBL8669690 | 0.79 | UTS2R (0.39) | DRD2 | |
| SCHEMBL8487928 | 0.79 | SCN1A (0.36) | — | |
| SCHEMBL8485120 | 0.78 | TSHR (0.36) | OPRK1HTR1ADRD2 | |
| SCHEMBL8479611 | 0.78 | SCN1A (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | claimed |
| US-5883099-A | TREATMENT OF ATHERSCLEROSIS, PANCREATITIS OBESITY OR HYPERGLYCEMIA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |