Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 1/20 | 0.32 |
| ▸ | RARG | P13631 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.30 |
| ▸ | GSK3B | P49841 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28444641 | 0.86 | RARA (0.31) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL8486887 | 0.83 | MAPT (0.33) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL29057754 | 0.79 | ALDH1A1 (0.33) | ALDH1A1NPC1RAB9AGSK3B | |
| SCHEMBL27641916 | 0.79 | SMN1; SMN2 (0.35) | RARARARBRARGRXRANR2E1 | |
| SCHEMBL27656088 | 0.79 | MEN1 (0.40) | LMNAALDH1A1TSHR | |
| SCHEMBL28536651 | 0.79 | CES1 (0.32) | CES1 | |
| SCHEMBL5320073 | 0.79 | LMNA (0.36) | LMNARARARARBRARGRXRA | |
| SCHEMBL8502416 | 0.78 | FFAR1 (0.37) | LMNAALDH1A1RAB9A | |
| Hydrogen Sulfide SCHEMBL27540779 | 0.78 | LMNA (0.36) | LMNARARARARBRARGRXRA | |
| SCHEMBL16033820 | 0.75 | HSD11B1 (0.33) | LMNARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108530357-A | Acridine D-A type thermal activation delayed fluorescence material, preparation method and application | 中国科学院宁波材料技术与工程研究所 | 2018-09-14 | — | — | CN | disclosed |