Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNE1 | P15382 | 3/20 | 0.34 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.30 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6966585 | 0.90 | KCNE1 (0.32) | KCNE1KCNQ1LMNAGAABCHE | |
| SCHEMBL6980167 | 0.90 | KCNE1 (0.34) | KCNE1KCNQ1LMNAGAAPTPN1 | |
| SCHEMBL6981132 | 0.84 | RAB9A (0.39) | KCNE1KCNQ1GAAMAPTL3MBTL1 | |
| SCHEMBL6968430 | 0.84 | MCHR1 (0.37) | KCNE1KCNQ1MAOB | |
| SCHEMBL6968820 | 0.83 | KCNH2 (0.44) | LMNAMAPTMAPK1MAOB | |
| SCHEMBL979035 | 0.80 | KCNE1 (0.38) | KCNE1KCNQ1LMNAGAAPTPN1 | |
| SCHEMBL8868743 | 0.80 | KCNE1 (0.38) | KCNE1KCNQ1LMNAGAAPTPN1 | |
| SCHEMBL8867575 | 0.80 | KCNE1 (0.38) | KCNE1KCNQ1LMNAGAAPTPN1 | |
| SCHEMBL6969588 | 0.79 | PPARG (0.47) | MAPTTDP1 | |
| SCHEMBL6976223 | 0.79 | PPARG (0.37) | LMNAL3MBTL1MAOBLTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |