Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 5/20 | 0.39 |
| ▸ | DRD3 | P35462 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8491631 | 0.85 | MAPK1 (0.51) | DRD2DRD3KMT2APOLBHTR7 | |
| SCHEMBL8487210 | 0.85 | HTR7 (0.44) | DRD2DRD3KMT2APOLBHTR1A | |
| SCHEMBL8488928 | 0.80 | ALDH1A1 (0.44) | FAAHMEN1KMT2AMCHR1POLB | |
| SCHEMBL7373473 | 0.74 | HTR7 (0.45) | DRD2DRD3MEN1KMT2APOLB | |
| SCHEMBL7370826 | 0.73 | HTR7 (0.43) | DRD2DRD3MEN1KMT2APOLB | |
| SCHEMBL8488927 | 0.73 | FAAH (0.39) | FAAHDRD2DRD3MEN1KMT2A | |
| SCHEMBL7377179 | 0.72 | HTR7 (0.41) | DRD2DRD3MEN1KMT2APOLB | |
| SCHEMBL8489110 | 0.71 | MAPK1 (0.51) | DRD2DRD3KMT2APOLBHTR1A | |
| SCHEMBL8488822 | 0.71 | DRD2 (0.43) | DRD2DRD3POLBLMNAHTR7 | |
| SCHEMBL8541317 | 0.70 | DRD2 (0.41) | DRD2DRD3POLBLMNAHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929074-A | VSODILATOR, ANTIALLERGIC AND ANTIPLATELET AGENTS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-07-27 | — | — | US | disclosed |
| US-5728702-A | BRONCHODILATOR AGENTS, ANTIALLERGENS OR ANTIPLATELET DRUGGS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1998-03-17 | — | — | US | disclosed |