Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.35 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.35 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL418180 | 0.81 | SMN1; SMN2 (0.62) | LMNAKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL415485 | 0.80 | KDM4E (0.55) | LMNAKDM4ESMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL7729548 | 0.80 | KDM4E (0.50) | LMNAKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL2921221 | 0.77 | JAK2 (0.57) | LMNAKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL7666259 | 0.77 | KDM4E (0.47) | LMNAKDM4ESMN1; SMN2ALDH1A1CDK2 | |
| Ethylene SCHEMBL27448159 | 0.77 | KDM4E (0.51) | LMNAKDM4ESMN1; SMN2ALDH1A1ALOX15 | |
| SCHEMBL11957361 | 0.77 | SMN1; SMN2 (0.49) | LMNAKDM4ESMN1; SMN2ALDH1A1TSHR | |
| Biphenyl SCHEMBL7862554 | 0.75 | F2 (0.61) | LMNAKDM4ESMN1; SMN2F2ALDH1A1 | |
| SCHEMBL8913939 | 0.74 | KDM4E (0.45) | LMNAKDM4ESMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL322998 | 0.73 | LMNA (0.58) | LMNASMN1; SMN2F2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939559-A | HERBICIDES FROM PYRAZOLE KETONES | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1999-08-17 | — | — | US | disclosed |