Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 12/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 3/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8889685 | 0.89 | CCNE1 (0.36) | NAAADHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8684141 | 0.89 | DHODH (0.33) | TSHRSMN1; SMN2DHODHTAS1R3TAS1R1 | |
| SCHEMBL8492662 | 0.88 | LMNA (0.43) | DHODHTAS1R3TAS1R1TAS1R2PDE2A | |
| SCHEMBL8492604 | 0.85 | DDR1 (0.37) | TSHRSMN1; SMN2DHODH | |
| SCHEMBL8492306 | 0.84 | CDK7 (0.39) | NAAADHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8890301 | 0.82 | TAS1R3 (0.33) | TSHRSMN1; SMN2DHODHTAS1R3TAS1R1 | |
| SCHEMBL7575147 | 0.81 | DHODH (0.34) | SMN1; SMN2DHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8664269 | 0.81 | DHODH (0.33) | DHODHPDE2A | |
| SCHEMBL8890152 | 0.81 | LMNA (0.36) | DHODHTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL8890477 | 0.81 | NR3C1 (0.38) | TSHRDHODHTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859283-A | TERTIARY-BUTYL 3-CYCLOALKYL-3-OXOPROPIONATE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1999-01-12 | — | — | US | disclosed |
| US-5804532-A | REACTING A BENZOYL ISOXAZOLE WITH A BASE | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-09-08 | — | — | US | disclosed |
| US-5747424-A | HEATING AN AROMATIC DIKETONE WITH A SALT OF HYDROXYLAMINE IN A SOLVENT | RHONE-POULENC AGRICULTURE LTD. (GB) | 1998-05-05 | — | — | US | disclosed |
| US-5656573-A | Herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-12 | — | — | US | disclosed |
| US-5650533-A | Intermediates to herbicidal 4-substituted isoxazoles | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-07-22 | — | — | US | disclosed |