Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.36 |
| ▸ | CDK2 | P24941 | 2/20 | 0.36 |
| ▸ | GSK3B | P49841 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 5/20 | 0.32 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.32 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.32 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.32 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890304 | 0.91 | DHODH (0.34) | PTGDR2TAS1R3TAS1R1TAS1R2DHODH | |
| SCHEMBL8890477 | 0.90 | NR3C1 (0.38) | CCNE1CDK2GSK3BTAS1R3TAS1R1 | |
| SCHEMBL8489199 | 0.89 | NAAA (0.38) | NAAATAS1R3TAS1R1TAS1R2DHODH | |
| SCHEMBL8891781 | 0.87 | DHODH (0.36) | KMT2ATAS1R3TAS1R1TAS1R2DHODH | |
| SCHEMBL8891637 | 0.85 | LMNA (0.34) | CCNE1CDK2GSK3BKMT2ATAS1R3 | |
| SCHEMBL8891108 | 0.84 | NR3C1 (0.32) | TAS1R3TAS1R1TAS1R2DHODHJAK2 | |
| SCHEMBL8892991 | 0.83 | NPC1 (0.38) | TAS1R3TAS1R1TAS1R2DHODHPDE2A | |
| SCHEMBL8890973 | 0.83 | NAAA (0.32) | NAAAPTGDR2DHODHJAK2JAK1 | |
| SCHEMBL8891351 | 0.83 | EPHX2 (0.36) | KMT2APTGDR2 | |
| SCHEMBL7575147 | 0.82 | DHODH (0.34) | TAS1R3TAS1R1TAS1R2DHODHPDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1997028136-A1 | BENZOYLISOXAZOLES AND 2-CYANO-1,3-DIONE DERIVATIVES AND THEIR USE AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD. (GB) | 1997-08-07 | — | — | WO | disclosed |