Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | TACR1 | P25103 | 1/20 | 0.56 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.55 |
| ▸ | HTR1A | P08908 | 2/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.54 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.54 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.54 |
| ▸ | MAOA | P21397 | 2/20 | 0.54 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.54 |
| ▸ | HTR1B | P28222 | 2/20 | 0.54 |
| ▸ | HTR2A | P28223 | 2/20 | 0.54 |
| ▸ | HTR2C | P28335 | 2/20 | 0.54 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.54 |
| ▸ | HTR7 | P34969 | 2/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24723809 | 0.83 | CDK4 (0.77) | CDK4KMT2AMEN1LMNAGAA | |
| SCHEMBL18498486 | 0.81 | MEN1 (0.59) | KMT2AMEN1LMNAHTR1AADRA2A | |
| SCHEMBL2992112 | 0.80 | HTR1A (0.50) | CDK4KMT2AMEN1LMNAGAA | |
| SCHEMBL6921417 | 0.79 | HTR1A (0.49) | CDK4KMT2AMEN1LMNATAAR1 | |
| SCHEMBL12837476 | 0.78 | LMNA (0.66) | CDK4KMT2AMEN1LMNAGAA | |
| SCHEMBL4064579 | 0.78 | NPC1 (0.58) | KMT2AMEN1ALDH1A1HPGDPOLB | |
| SCHEMBL1093103 | 0.76 | ALDH1A1 (0.59) | CDK4KMT2AMEN1LMNAGAA | |
| SCHEMBL30230046 | 0.76 | TACR1 (0.69) | CDK4KMT2AMEN1LMNAGAA | |
| SCHEMBL8345148 | 0.76 | TACR1 (0.69) | CDK4KMT2AMEN1LMNAGAA | |
| SCHEMBL8345144 | 0.76 | TACR1 (0.69) | CDK4KMT2AMEN1LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981755-A | Tachykinin antagonists | WARNER-LAMBERT COMPANY (US) | 1999-11-09 | — | — | US | disclosed |
| US-5594022-A | CARBAMATES | WARNER-LAMBERT COMPANY (US) | 1997-01-14 | — | — | US | disclosed |