Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.34 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129279 | 0.85 | CALM1 (0.46) | ALDH1A1CALM1RAB9AIDH1ACMSD | |
| SCHEMBL8123568 | 0.81 | NR1H2 (0.40) | ALDH1A1CALM1RAB9AMEN1KMT2A | |
| SCHEMBL38661320 | 0.74 | ALDH1A1 (0.60) | ALDH1A1CALM1SLC22A2RAB9AMEN1 | |
| SCHEMBL10945065 | 0.73 | ALDH1A1 (0.48) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10965408 | 0.73 | GSTP1 (0.37) | ALDH1A1RAB9AMEN1KMT2ANPC1 | |
| SCHEMBL10814257 | 0.73 | ALDH1A1 (0.52) | ALDH1A1CALM1SLC22A2RAB9AMEN1 | |
| SCHEMBL16640685 | 0.72 | CALM1 (0.63) | ALDH1A1CALM1SLC22A2RAB9AMEN1 | |
| SCHEMBL9952077 | 0.72 | FFAR1 (0.43) | LTA4H | |
| SCHEMBL8130799 | 0.69 | NPC1 (0.41) | ALDH1A1CALM1RAB9AMEN1KMT2A | |
| SCHEMBL5496841 | 0.68 | TSHR (0.43) | IDH1ACMSDLTA4HTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5955616-A | PROSTAGLANDIN INHIBITORS | SHIONOGI & CO., LTD. (JP) | 1999-09-21 | — | — | US | disclosed |