Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.43 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 2/20 | 0.40 |
| ▸ | LTB4R | Q15722 | 7/20 | 0.37 |
| ▸ | LTB4R2 | Q9NPC1 | 7/20 | 0.37 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ACACA | Q13085 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8129279 | 0.78 | CALM1 (0.46) | LTA4H | |
| SCHEMBL8123568 | 0.74 | NR1H2 (0.40) | — | |
| SCHEMBL8489407 | 0.72 | ALDH1A1 (0.36) | LTA4H | |
| SCHEMBL6904351 | 0.71 | FFAR1 (0.61) | FFAR1S1PR5S1PR1LTB4RLTB4R2 | |
| SCHEMBL4363303 | 0.67 | FFAR1 (0.56) | FFAR1S1PR5S1PR1LTB4RLTB4R2 | |
| SCHEMBL14114020 | 0.67 | FFAR1 (0.62) | FFAR1S1PR5S1PR1LTB4RLTB4R2 | |
| SCHEMBL864142 | 0.66 | FFAR1 (0.49) | FFAR1S1PR5S1PR1LTB4RLTB4R2 | |
| SCHEMBL9952370 | 0.66 | ALDH1A1 (0.44) | LTA4H | |
| SCHEMBL8939754 | 0.66 | LTA4H (0.48) | LTA4H | |
| SCHEMBL12351783 | 0.66 | FFAR1 (0.60) | FFAR1S1PR5S1PR1LTB4RLTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2655362-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | Abbvie Inc. (US) | 2013-10-30 | — | — | EP | disclosed |
| WO-2012087833-A1 | HEPATITIS C INHIBITORS AND USES THEREOF | ABBOTT LABORATORIES (US) | 2012-06-28 | — | — | WO | disclosed |