Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 3/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.36 |
| ▸ | HTR6 | P50406 | 6/20 | 0.35 |
| ▸ | DUT | P33316 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.33 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
| ▸ | FLT4 | P35916 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.32 |
| ▸ | TEK | Q02763 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14889035 | 0.81 | DGAT1 (0.34) | DGAT1 | |
| SCHEMBL20746061 | 0.78 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL25214568 | 0.76 | DGAT1 (0.36) | DGAT1 | |
| SCHEMBL23063436 | 0.76 | DGAT1 (0.35) | DGAT1ABCB1HTR6 | |
| SCHEMBL7843607 | 0.75 | ESR1 (0.47) | DGAT1LIMK2EGFRIGF1RSRC | |
| SCHEMBL8524880 | 0.74 | DGAT1 (0.34) | DGAT1HTR6 | |
| SCHEMBL8372860 | 0.73 | NR1I2 (0.41) | — | |
| SCHEMBL8376148 | 0.73 | C1S (0.40) | — | |
| SCHEMBL25255001 | 0.73 | FBP1 (0.39) | — | |
| SCHEMBL27265900 | 0.72 | ALDH1A1 (0.40) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999006377-A1 | DERIVATIVES OF 1-((3,3-DIMETHYL-3-SILABUTOXY)METHYL)-2-(PHENYLSULFONYL)IMIDAZOLE | GLIATECH, INC. (US) | 1999-02-11 | — | — | WO | disclosed |
| WO-1999006377-A1 | DERIVATIVES OF 1-((3,3-DIMETHYL-3-SILABUTOXY)METHYL)-2-(PHENYLSULFONYL)IMIDAZOLE | GLIATECH, INC. (US) | 1999-02-11 | — | — | WO | disclosed |