Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | FPR2 | P25090 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL676305 | 0.91 | ALDH1A1 (0.46) | ALDH1A1GAASMN1; SMN2XDHTLR8 | |
| SCHEMBL28080934 | 0.84 | LMNA (0.37) | ALDH1A1GAALMNACYP1A2AGTR1 | |
| SCHEMBL27681963 | 0.80 | ALDH1A1 (0.38) | ALDH1A1GAATLR8 | |
| SCHEMBL182827 | 0.79 | MAPT (0.46) | ALDH1A1GAALMNASMN1; SMN2MEN1 | |
| SCHEMBL28026234 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAATLR8MAPT | |
| SCHEMBL4888071 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAALMNAXDHMEN1 | |
| SCHEMBL27911608 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAACYP1A2XDHPOLB | |
| SCHEMBL27822844 | 0.79 | ALDH1A1 (0.39) | ALDH1A1GAASMN1; SMN2XDHMEN1 | |
| SCHEMBL27822790 | 0.79 | ALDH1A1 (0.42) | ALDH1A1GAAXDHTLR8MAPT | |
| SCHEMBL8674 | 0.78 | CA2 (0.46) | ALDH1A1LMNACYP1A2POLBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999051598-A1 | SUBSTITUTED 9H-PYRIDINO[2,3-b]INDOLE AND 9H-PYRIMIDINO[4,5-b]INDOLE DERIVATIVES: SELECTIVE NEUROPEPTIDE y RECEPTOR LIGANDS | NEUROGEN CORPORATION (US) | 1999-10-14 | — | — | WO | claimed |