Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8492022 | 0.80 | LTA4H (0.34) | SMN1; SMN2 | |
| SCHEMBL7207584 | 0.77 | DRD2 (0.47) | HPGDMAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7211962 | 0.77 | HPGD (0.33) | HPGDL3MBTL1 | |
| SCHEMBL8492013 | 0.76 | CYP2C19 (0.33) | MAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL7207588 | 0.72 | SLC6A9 (0.32) | — | |
| SCHEMBL7467290 | 0.70 | — | — | |
| SCHEMBL7467283 | 0.68 | KDM4E (0.32) | SMN1; SMN2 | |
| SCHEMBL7207522 | 0.68 | MEN1 (0.31) | HPGDMAPK1L3MBTL1 | |
| SCHEMBL5088326 | 0.64 | TAAR1 (0.50) | HPGDL3MBTL1 | |
| SCHEMBL8659616 | 0.63 | CACNA2D1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958965-A | TREATMENT OF DISEASES ATTENDING DISTURBANCES IN THE SEROTINERGIC SYSTEMS, SUCH AS ANXIETY, STRESS, DEPRESSION, SEXUAL DYSFUNCTIONS AND SLEEP DISTURBANCES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-09-28 | — | — | US | disclosed |