SCHEMBL8492619

SCHEMBL8492619

O=c1oc2c(O)cccc2c(O)c1O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ATP1A1 P05023 2/20 0.56
ATP1B1 P05026 2/20 0.56
ATP1A3 P13637 2/20 0.56
ATP1B2 P14415 2/20 0.56
ATP1A2 P50993 2/20 0.56
ATP1B3 P54709 2/20 0.56
FXYD2 P54710 2/20 0.56
ATP1A4 Q13733 2/20 0.56
MAOA P21397 11/20 0.53
EGFR P00533 2/20 0.53
LOXL2 Q9Y4K0 1/20 0.46
ADORA3 P0DMS8 3/20 0.45
ADORA2A P29274 3/20 0.45
ADORA1 P30542 3/20 0.45
MAOB P27338 2/20 0.45
CA12 O43570 2/20 0.45
CA1 P00915 2/20 0.45
CA2 P00918 2/20 0.45
CA9 Q16790 2/20 0.45
ESR2 Q92731 3/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8493330 0.79 MAOA (0.58) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL11477475 0.79 ADORA3 (0.53) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL8492888 0.79 MAOA (0.58) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL10789961 0.78 ESR2 (0.53) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL10791657 0.77 MAOA (0.50) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL12359896 0.77 MAOA (0.69) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL10846874 0.77 MAOA (0.50) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL10789975 0.77 MAOA (0.50) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL7228336 0.77 ATP1A1 (0.79) ATP1A1ATP1B1ATP1A3ATP1B2ATP1A2
SCHEMBL8496221 0.77 MAOA (0.54) MAOACA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1923193-A Application of cumarin kind compound in preparation of antiphlogistic and analgetic medicine UNIV PLA 2ND MILITARY MEDICAL (CN) 2007-03-07 CN disclosed
EP-0598117-B1 BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK & CHEMICALS (JP) 1999-06-30 EP disclosed
US-5428059-A Benzopyran derivatives and an anti-allergic agent possessing the same as the active ingredient DAINIPPON INK & CHEMICALS, INC. (JP) 1995-06-27 US disclosed
EP-0598117-A1 BENZOPYRAN DERIVATIVE AND ANTIALLERGIC AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT DAINIPPON INK AND CHEMICALS, INC. (JP) 1994-05-25 EP disclosed