Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 11/20 | 0.54 |
| ▸ | CACNA1H | O95180 | 6/20 | 0.54 |
| ▸ | LSS | P48449 | 1/20 | 0.54 |
| ▸ | LTA4H | P09960 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074697 | 0.79 | KDM4E (0.59) | CACNA1BCACNA1HLSSLTA4HKDM4E | |
| SCHEMBL5221545 | 0.77 | KDM4E (0.65) | CACNA1BCACNA1HLSSKDM4EALDH1A1 | |
| SCHEMBL13886633 | 0.77 | LTA4H (0.83) | CACNA1BCACNA1HLSSLTA4HKDM4E | |
| SCHEMBL8496349 | 0.77 | POLB (0.39) | LTA4H | |
| SCHEMBL9671156 | 0.74 | KDM4E (0.83) | LSSLTA4HKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL4632841 | 0.73 | LSS (0.79) | CACNA1BLSSLTA4HKDM4EALDH1A1 | |
| SCHEMBL95237 | 0.73 | GAA (0.48) | LTA4HALDH1A1 | |
| SCHEMBL8498200 | 0.71 | FFAR1 (0.45) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL195415 | 0.71 | CYP1A2 (0.55) | LTA4HSMN1; SMN2 | |
| SCHEMBL7363062 | 0.71 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5932543-A | INHIBITING FUNGAL AND PARASITIC ACTIVITY | ELI LILLY AND COMPANY (US) | 1999-08-03 | — | — | US | disclosed |