SCHEMBL849890

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1907911	0.82	ALDH1A1 (0.48)	TSHRALDH1A1HSD17B10TRPV1MAPT
	SCHEMBL147828	0.81	CA2 (0.52)	CA2CA1ENPP2MGLLTSHR
	SCHEMBL25968742	0.78	CA2 (0.54)	CA2CA1ENPP2MGLLTSHR
	SCHEMBL75746	0.77	ALDH1A1 (0.46)	TSHRALDH1A1HSD17B10TRPV1MAPT
	SCHEMBL1393204	0.76	CA1 (0.59)	CA2CA1ENPP2MGLLMAPT
	SCHEMBL6610143	0.76	CA1 (0.48)	CA2CA1ENPP2MGLLMAPT
	SCHEMBL17099758	0.74	CA2 (0.45)	CA2CA1ENPP2MGLLTSHR
	SCHEMBL26464057	0.74	CA2 (0.50)	CA2CA1ENPP2MGLLTSHR
	SCHEMBL4456125	0.74	ALDH1A1 (0.43)	TSHRALDH1A1HSD17B10TRPV1MAPT
	SCHEMBL27233488	0.73	CA2 (0.48)	CA2CA1ENPP2MGLLTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.