Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | BAX | Q07812 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1907911 | 0.88 | ALDH1A1 (0.48) | ALDH1A1TSHRHSD17B10TRPV1KDM4E | |
| SCHEMBL10932957 | 0.85 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10TRPV1ESR1 | |
| SCHEMBL10703814 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TSHRHSD17B10TRPV1ESR1 | |
| SCHEMBL4456125 | 0.79 | ALDH1A1 (0.43) | ALDH1A1TSHRHSD17B10TRPV1CETP | |
| SCHEMBL221511 | 0.78 | MAPT (0.52) | ALDH1A1TSHRHSD17B10ESR1ESR2 | |
| SCHEMBL16302584 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRHSD17B10TRPV1KDM4E | |
| SCHEMBL3945050 | 0.77 | TRPV1 (0.51) | ALDH1A1TSHRHSD17B10TRPV1MEN1 | |
| SCHEMBL2029020 | 0.77 | ALDH1A1 (0.44) | ALDH1A1TSHRHSD17B10TRPV1MEN1 | |
| SCHEMBL2707618 | 0.77 | TRPV1 (0.45) | ALDH1A1TSHRHSD17B10TRPV1MEN1 | |
| SCHEMBL12403373 | 0.77 | CA1 (0.50) | ALDH1A1TSHRHSD17B10TRPV1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129412-B2 | Hydantoin derivatives useful as metalloproteinase inhibitors | ASTRAZENECA AB (SE) | 2012-03-06 | — | — | US | disclosed |
| EP-1828166-B1 | HYDANTOIN DERIVATIVES USEFUL AS METALLOPROTEINASE INHIBITORS | ASTRAZENECA AB (SE) | 2009-07-22 | — | — | EP | disclosed |
| US-20080280950-A1 | Hydantoin Derivatives Useful as Metalloproteinase Inhibitors | ASTRAZENECA AB (SE) | 2008-11-13 | — | — | US | disclosed |
| US-4551448-A | INSECTICIDES, MITICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-11-05 | — | — | US | disclosed |
| EP-0091598-B1 | FLUORO-ETHOXYPHENYL-(DI)-THIOPHOSPHORIC-ACID ESTERS, PROCESS FOR THEIR PREPARATION AND THEIR USE AS PESTICIDES | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0091598-A2 | Fluoro-ethoxyphenyl-(di)-thiophosphoric-acid esters, process for their preparation and their use as pesticides | BASF Aktiengesellschaft (DE) | 1983-10-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280950-A1 | Hydantoin Derivatives Useful as Metalloproteinase Inhibitors | MMP3, MMP9, MMP2 | ALDH1A1 528/4885TSHR 3130/4885HSD17B10 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.