Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | HTR1D | P28221 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CCR5 | P51681 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.36 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501813 | 0.80 | SMN1; SMN2 (0.37) | L3MBTL1MAPK1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL6697273 | 0.76 | MAPK1 (0.57) | HTR1AMAPK1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL5504851 | 0.73 | TSHR (0.39) | L3MBTL1MAPK1ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL7361998 | 0.72 | TSHR (0.38) | L3MBTL1MAPK1ALDH1A1THRBSMN1; SMN2 | |
| SCHEMBL28271058 | 0.71 | AAK1 (0.44) | L3MBTL1GAAAAK1 | |
| SCHEMBL2291108 | 0.71 | CTSK (0.44) | L3MBTL1GAAAAK1CYP1A2CYP3A4 | |
| SCHEMBL28022205 | 0.71 | AAK1 (0.44) | L3MBTL1GAAAAK1 | |
| Ammonia Solution, Strong SCHEMBL28118901 | 0.70 | AAK1 (0.43) | L3MBTL1GAAAAK1 | |
| SCHEMBL28246353 | 0.70 | AAK1 (0.42) | L3MBTL1GAAAAK1 | |
| SCHEMBL8893618 | 0.70 | KIF11 (0.44) | AAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915888-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | Takeda Chemical Industries, Ltd. (JP) | 1999-05-19 | — | — | EP | disclosed |
| WO-1997040051-A1 | FUSED IMIDAZOPYRIDINE DERIVATIVES AS ANTIHYPERLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-10-30 | — | — | WO | disclosed |