Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CKS1B | P61024 | 1/20 | 0.38 |
| ▸ | SKP1 | P63208 | 1/20 | 0.38 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 3/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664872 | 0.96 | SMPD2 (0.37) | CKS1BSKP1SKP2ALDH1A1RAB9A | |
| SCHEMBL8717984 | 0.88 | CCR3 (0.42) | POLBDRD2HTR1ADRD3 | |
| SCHEMBL8712539 | 0.86 | CCR3 (0.42) | POLBDRD2HTR1ADRD3 | |
| SCHEMBL8593680 | 0.85 | POLB (0.42) | ALDH1A1POLBDRD2DRD4DRD3 | |
| SCHEMBL8712881 | 0.84 | POLB (0.35) | POLBDRD2HTR1ADRD4DRD3 | |
| SCHEMBL8665881 | 0.84 | DRD2 (0.37) | POLBDRD2DRD4DRD3 | |
| SCHEMBL8665519 | 0.84 | CCR3 (0.40) | DRD2HTR1A | |
| SCHEMBL8648478 | 0.83 | CCNE1 (0.37) | ALDH1A1POLBCNR1HTR2ADRD3 | |
| SCHEMBL8651966 | 0.83 | SLC6A12 (0.36) | POLBCNR1CNR2DRD2DRD4 | |
| SCHEMBL8666097 | 0.82 | DRD2 (0.36) | POLBDRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5739135-A | PREVENTING OR TREATING ATHEROSCLEROSIS, PANCREATITIS SECONDARY TO HYPERTRIGLYCERIDEMIA, HYPERGLYCEMIA, OBESITY | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-04-14 | — | — | US | disclosed |