Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD2 | O60906 | 1/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.37 |
| ▸ | CKS1B | P61024 | 1/20 | 0.35 |
| ▸ | SKP1 | P63208 | 1/20 | 0.35 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8713182 | 0.96 | CKS1B (0.38) | CKS1BSKP1SKP2POLBELANE | |
| SCHEMBL8665881 | 0.89 | DRD2 (0.37) | SMPD3POLB | |
| SCHEMBL8665519 | 0.88 | CCR3 (0.40) | KDM5A | |
| SCHEMBL8666097 | 0.87 | DRD2 (0.36) | SMPD3POLBMTNR1AMTNR1B | |
| SCHEMBL8665528 | 0.86 | CCR3 (0.40) | KDM5A | |
| SCHEMBL8665587 | 0.85 | AKT1 (0.36) | SMPD3POLB | |
| SCHEMBL8717984 | 0.84 | CCR3 (0.42) | POLBKDM5A | |
| SCHEMBL8501237 | 0.83 | MTTP (0.36) | POLB | |
| SCHEMBL8593680 | 0.82 | POLB (0.42) | POLBALDH1A1 | |
| SCHEMBL8712539 | 0.82 | CCR3 (0.42) | POLBKDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |