Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 2/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 3/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.40 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.38 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 2/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8501430 | 0.88 | ESR1 (0.46) | AKR1C3AKR1C2ESR1ESR2GRM2 | |
| SCHEMBL8497579 | 0.88 | SMN1; SMN2 (0.42) | AKR1C3AKR1C2ESR1ESR2CYP1A2 | |
| SCHEMBL8497439 | 0.85 | ESR1 (0.49) | AKR1C3AKR1C2ESR1ESR2MTNR1A | |
| SCHEMBL8502205 | 0.85 | MTNR1A (0.43) | AKR1C3AKR1C2ESR1ESR2CYP1A2 | |
| SCHEMBL8501462 | 0.85 | ESR1 (0.47) | ESR1ESR2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL8501243 | 0.84 | KDM4E (0.39) | ESR1ESR2PTGS2 | |
| SCHEMBL7190395 | 0.83 | CYP1A2 (0.42) | AKR1C3AKR1C2ESR1ESR2PRKCZ | |
| SCHEMBL7187740 | 0.83 | FFAR1 (0.50) | AKR1C3AKR1C2ESR1CYP1A2CYP3A4 | |
| SCHEMBL7928746 | 0.82 | DHFR (0.41) | ESR1ESR2CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8497702 | 0.82 | ESR1 (0.49) | ESR1ESR2CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |