Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 10/20 | 0.46 |
| ▸ | ESR2 | Q92731 | 9/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8497579 | 0.93 | SMN1; SMN2 (0.42) | ESR1ESR2AKR1C3AKR1C2GRM2 | |
| SCHEMBL8501462 | 0.90 | ESR1 (0.47) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL8501243 | 0.89 | KDM4E (0.39) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL8497867 | 0.89 | ESR1 (0.57) | ESR1ESR2 | |
| SCHEMBL8497439 | 0.89 | ESR1 (0.49) | ESR1ESR2AKR1C3AKR1C2KDM4E | |
| SCHEMBL8501225 | 0.88 | ESR1 (0.43) | ESR1ESR2AKR1C3AKR1C2GRM2 | |
| SCHEMBL8501413 | 0.88 | AKR1C3 (0.42) | ESR1ESR2AKR1C3AKR1C2GRM2 | |
| SCHEMBL8497550 | 0.86 | ESR1 (0.49) | ESR1ESR2KDM4EALDH1A1MAPT | |
| SCHEMBL8502205 | 0.86 | MTNR1A (0.43) | ESR1ESR2AKR1C3AKR1C2TDP1 | |
| SCHEMBL8497879 | 0.86 | KMT2A (0.42) | ESR1ESR2AKR1C3AKR1C2GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | claimed |
| US-5916916-A | USEFUL AS SELECTIVE ESTROGEN RECEPTOR MODULATORS. | ELI LILLY AND COMPANY (US) | 1999-06-29 | — | — | US | disclosed |