Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.47 |
| ▸ | SCD | O00767 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CBFB | Q13951 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17702662 | 0.86 | NPBWR1 (0.61) | NPBWR1SCDMEN1KMT2ACBFB | |
| SCHEMBL4318643 | 0.85 | HDAC6 (0.46) | MEN1KMT2AALDH1A1HSP90AA1ESR2 | |
| SCHEMBL14493326 | 0.85 | MAPT (0.51) | MEN1KMT2AALDH1A1HSP90AA1ESR2 | |
| Hydrochloric Acid SCHEMBL32662723 | 0.83 | ALDH1A1 (0.44) | MEN1KMT2AALDH1A1HSP90AA1ESR2 | |
| SCHEMBL11371864 | 0.82 | TAS2R14 (0.54) | MEN1KMT2AALDH1A1HSP90AA1ESR2 | |
| SCHEMBL10969202 | 0.81 | FABP6 (0.47) | NPBWR1SCDMEN1KMT2ACBFB | |
| SCHEMBL8498390 | 0.81 | NPBWR1 (0.46) | NPBWR1SCDMEN1KMT2ACBFB | |
| SCHEMBL8501872 | 0.81 | NPBWR1 (0.46) | NPBWR1SCDMEN1KMT2ACBFB | |
| SCHEMBL1108964 | 0.81 | TYMS (0.48) | NPBWR1MEN1KMT2AALDH1A1HSP90AA1 | |
| SCHEMBL15381368 | 0.81 | POLB (0.54) | MEN1KMT2AALDH1A1HSP90AA1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0946559-A2 | IMIDAZOPYRIDAZINES | Byk Gulden Lomberg Chemische Fabrik GmbH (DE) | 1999-10-06 | — | — | EP | disclosed |
| WO-1998028299-A2 | IMIDAZOPYRIDAZINES | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1998-07-02 | — | — | WO | disclosed |