Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.31 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504953 | 0.89 | ALDH1A1 (0.38) | ALDH1A1HPGDHTTNPSR1KDM4E | |
| SCHEMBL8501881 | 0.70 | ALDH1A1 (0.38) | ALDH1A1HTTKDM4EMAPTMEN1 | |
| SCHEMBL28502249 | 0.69 | ALDH1A1 (0.44) | ALDH1A1HTTKDM4ETDP1IDO1 | |
| SCHEMBL8501886 | 0.68 | NPBWR1 (0.45) | NPSR1MAPTKMT2ATP53NPC1 | |
| SCHEMBL7581125 | 0.67 | LMNA (0.36) | ALDH1A1HPGDKDM4EMAPTMEN1 | |
| SCHEMBL8504945 | 0.67 | NPBWR1 (0.39) | ALDH1A1HPGDHTTNPSR1IDO1 | |
| SCHEMBL8502103 | 0.65 | BDKRB1 (0.37) | ALDH1A1HPGDHTTNPSR1KDM4E | |
| SCHEMBL8526361 | 0.65 | MAPT (0.43) | ALDH1A1HTTNPSR1MAPTMEN1 | |
| SCHEMBL8504948 | 0.61 | ALDH1A1 (0.37) | ALDH1A1HTTKDM4EMAPTMEN1 | |
| SCHEMBL10633273 | 0.61 | NPC1 (0.50) | ALDH1A1HTTKDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |