Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | NEK2 | P51955 | 1/20 | 0.39 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502482 | 0.76 | HPGD (0.48) | MAPTALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8504693 | 0.75 | L3MBTL1 (0.38) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL8503177 | 0.74 | POLB (0.38) | MAPTHTTNPSR1ALDH1A1MEN1 | |
| SCHEMBL8505745 | 0.72 | KMT2A (0.44) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL8502094 | 0.72 | MEN1 (0.45) | MAPTTP53ALDH1A1MEN1KMT2A | |
| SCHEMBL8505812 | 0.71 | ADRB2 (0.42) | MAPTHTTNPSR1TP53ALDH1A1 | |
| SCHEMBL30785051 | 0.71 | MAPT (0.69) | MAPTHTTNPSR1TP53ALDH1A1 | |
| SCHEMBL27501601 | 0.70 | NPBWR1 (0.56) | MAPTALDH1A1LMNA | |
| SCHEMBL8526363 | 0.70 | MAPT (0.44) | MAPTHTTNPSR1TP53ALDH1A1 | |
| SCHEMBL8501886 | 0.70 | NPBWR1 (0.45) | MAPTNPSR1TP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |