Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | LIPE | Q05469 | 13/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.53 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.53 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.53 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10944778 | 0.86 | LMNA (0.62) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL3940686 | 0.86 | MRGPRX4 (0.53) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL10667784 | 0.84 | L3MBTL1 (0.56) | — | |
| SCHEMBL13506423 | 0.83 | HPGD (0.66) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL11605293 | 0.83 | L3MBTL1 (0.61) | — | |
| SCHEMBL8413343 | 0.83 | SMN1; SMN2 (0.62) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL11351938 | 0.81 | MAPT (0.69) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL11563026 | 0.81 | LMNA (0.56) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL20626652 | 0.81 | LIPE (0.67) | LMNARAB9ALIPEMAPTNPSR1 | |
| SCHEMBL4327207 | 0.81 | LMNA (0.73) | LMNARAB9ALIPEMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869681-A | PREPARING TRIAZOLINONE INTERMEDIATE BY HEATING HYDROCARBYLOXYCARBONYL-ISOSEMICARBAZIDE TO CYCLIZE | BAYER AKTIENGESELLSCHAFT (DE) | 1999-02-09 | — | — | US | disclosed |
| US-5767107-A | ADMINISTERING FRAGRANCES, FLAVORS, VITAMINS, AGRICULTURAL CHEMICALS AND DRUGS; BIODEGRADATION; TIME-RELEASE AGENTS | BASF CORPORATION (US) | 1998-06-16 | — | — | US | disclosed |
| US-5756719-A | Double emulsion techniques for making novel compositions containing gluten and polysaccharides that contain uronic acid residues useful for encapsulating fats, oils and solids | BASF CORPORATION (US) | 1998-05-26 | — | — | US | disclosed |
| US-5675017-A | REACTING VINY ETHER DERIVATIVE WITH HYDRZINE OR SUBSTITUTED HYDRAZINE TO FORM A CHEMICAL INTERMEDIATE, REACTING INTERMEDIATE WITH SUBSTITUTED HALIDE OR DIALKYL SULFATE | MONSANTO COMPANY (US) | 1997-10-07 | — | — | US | disclosed |
| US-5672715-A | Herbicidal substituted 3-aryl-pyrazoles | MONSANTO COMPANY (US) | 1997-09-30 | — | — | US | disclosed |
| US-4925947-A | AGRICULTURAL USE, SENSITIVE TO CROPS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-15 | — | — | US | disclosed |
| EP-0001473-B1 | HERBICIDAL HALOGENOMETHYL--PYRIDYLOXY-PHENOXY-ALKANECARBOXYLIC ACIDS AND DERIVATIVES, AND PROCESSES OF CONTROLLING UNWANTED PLANTS THEREWITH | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1988-07-27 | — | — | EP | disclosed |
| US-4555575-A | CHLORINATION OF A DISUBSTITUTED METHYL PYRIDINE HYDROCHLORIDE SALT | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-11-26 | — | — | US | disclosed |
| US-4508907-A | 2,3-Dichloro-5-trichloromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1985-04-02 | — | — | US | disclosed |
| EP-0107866-A2 | Trihalomethylpyridine compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-09 | — | — | EP | disclosed |
| US-4324627-A | CHLORINATION OF 3-METHYLPYRIDINE UNDER INFLUENCE OF ULTRA VIOLET LIGHT | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-04-13 | — | — | US | disclosed |
| US-4317913-A | Herbicidal pyridine compounds | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-03-02 | — | — | US | disclosed |
| EP-0021453-A2 | 2-Chloro-5-trichloromethylpyridine | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-01-07 | — | — | EP | disclosed |
| EP-0001473-A2 | Herbicidal halogenomethyl--pyridyloxy-phenoxy-alkanecarboxylic acids and derivatives, and processes of controlling unwanted plants therewith | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-04-18 | — | — | EP | disclosed |