Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 1/20 | 0.37 |
| ▸ | MPO | P05164 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 8/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8504731 | 0.83 | HPGDS (0.35) | — | |
| SCHEMBL8502519 | 0.81 | MRGPRX4 (0.36) | PARP1MRGPRX4 | |
| SCHEMBL8502116 | 0.81 | MEN1 (0.38) | PDE3AAR | |
| SCHEMBL8506458 | 0.81 | MRGPRX4 (0.37) | MRGPRX4 | |
| SCHEMBL8505814 | 0.78 | ADRB2 (0.42) | POLB | |
| SCHEMBL7585620 | 0.75 | CYP3A4 (0.55) | PARP1MRGPRX4CNR2HCAR2POLB | |
| SCHEMBL8505616 | 0.75 | L3MBTL1 (0.42) | MRGPRX4POLB | |
| SCHEMBL8502190 | 0.74 | GAA (0.38) | MRGPRX4PTGER1 | |
| SCHEMBL2342924 | 0.70 | DAO (0.46) | PARP1AR | |
| SCHEMBL8503180 | 0.70 | ALDH1A1 (0.37) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |