Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | WDR5 | P61964 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8502116 | 0.91 | MEN1 (0.38) | HPGDSALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL8502519 | 0.91 | MRGPRX4 (0.36) | HPGDSWDR5ALOX15ALDH1A1MEN1 | |
| SCHEMBL8506458 | 0.90 | MRGPRX4 (0.37) | HPGDSALOX15ALDH1A1MEN1KMT2A | |
| SCHEMBL8505814 | 0.87 | ADRB2 (0.42) | ALOX15ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL8503802 | 0.85 | MAPT (0.42) | ALDH1A1MEN1KMT2AMAPTUSP2 | |
| SCHEMBL8503702 | 0.83 | IL4I1 (0.37) | — | |
| SCHEMBL8505616 | 0.83 | L3MBTL1 (0.42) | ALDH1A1HTTMAPTUSP2L3MBTL1 | |
| SCHEMBL8502190 | 0.82 | GAA (0.38) | ALDH1A1MEN1KMT2AMAPTKDM4E | |
| SCHEMBL8503180 | 0.79 | ALDH1A1 (0.37) | WDR5ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL8501896 | 0.78 | NPC1 (0.38) | ALOX15ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5886178-A | ADMINISTERING OF A PROSTAGLANDIN G/H SYNTHASE INHIBITOR TO A PATIENT TO TREAT INFLAMMATORY OR AUTOIMMUNE DISEASES | SYNTEX (U.S.A.) INC. (US) | 1999-03-23 | — | — | US | disclosed |