Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNA5 | P22460 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8666046 | 0.94 | L3MBTL1 (0.34) | KCNA5TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL8679135 | 0.93 | L3MBTL1 (0.36) | KCNA5TSHRKMT2AKDM4EALDH1A1 | |
| SCHEMBL8500944 | 0.85 | MCHR1 (0.34) | KMT2A | |
| SCHEMBL8479387 | 0.84 | RORC (0.36) | ALDH1A1 | |
| SCHEMBL8665214 | 0.81 | MCHR1 (0.37) | — | |
| SCHEMBL8480060 | 0.81 | CCR3 (0.40) | KMT2A | |
| SCHEMBL8502233 | 0.75 | GAA (0.34) | KCNA5TSHRKDM4EALDH1A1PSEN1 | |
| SCHEMBL8504369 | 0.73 | HTT (0.31) | KCNA5L3MBTL1HTT | |
| SCHEMBL8593680 | 0.73 | POLB (0.42) | KMT2AKDM4EALDH1A1PSEN1PSEN2 | |
| SCHEMBL8664324 | 0.71 | NPY1R (0.35) | PSEN1PSEN2APH1BNCSTNAPH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5885983-A | ANTICHOLESTEROL AGENTS, ANTILIPOLYTIC AGENTS, ANTILIPEMIC AGENTS FOR TREATING HYPERLIPEMIA, ATHEROSCLEROSIS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1999-03-23 | — | — | US | disclosed |