Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 3/20 | 0.37 |
| ▸ | CCR3 | P51677 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD4 | P21917 | 3/20 | 0.36 |
| ▸ | SLC6A12 | P48065 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.33 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480060 | 0.96 | CCR3 (0.40) | MCHR1CCR3SLC6A12TMEM97SIGMAR1 | |
| SCHEMBL8500944 | 0.94 | MCHR1 (0.34) | MCHR1CCR3DRD2DRD4SLC6A12 | |
| SCHEMBL8665881 | 0.86 | DRD2 (0.37) | MCHR1DRD2DRD4AKT1CHRM1 | |
| SCHEMBL8668034 | 0.85 | CCR3 (0.37) | MCHR1CCR3DRD2DRD4SLC6A12 | |
| SCHEMBL8666097 | 0.84 | DRD2 (0.36) | MCHR1DRD2DRD4AKT1CHRM1 | |
| SCHEMBL8666046 | 0.84 | L3MBTL1 (0.34) | — | |
| SCHEMBL8679135 | 0.82 | L3MBTL1 (0.36) | — | |
| SCHEMBL8717803 | 0.82 | CCR3 (0.40) | MCHR1CCR3SLC6A12TMEM97SIGMAR1 | |
| SCHEMBL8504367 | 0.81 | KCNA5 (0.32) | — | |
| SCHEMBL8504377 | 0.80 | MCHR1 (0.34) | MCHR1CCR3DRD2DRD4SLC6A12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |