SCHEMBL8509652

SCHEMBL8509652

CC(=O)c1c(S)c(C(C)=O)c(Cl)c(C(C)=O)c1Cl

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
THRB P10828 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6512921 0.77 CYP3A4 (0.38) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL29150329 0.77 CES2 (0.42) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL8512478 0.75 KMT2A (0.39) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL6519336 0.75 CYP3A4 (0.36) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL6517438 0.75 CYP3A4 (0.36) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL29093706 0.70 HSD17B10 (0.32) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL8513517 0.69 CA12 (0.40) MEN1KMT2ACYP3A4HPGDLMNA
SCHEMBL8512654 0.68 THRB (0.32) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL8528421 0.68 CES2 (0.46) MEN1KMT2ATHRBCYP3A4HPGD
SCHEMBL5704372 0.68 CES2 (0.41) MEN1KMT2ATHRBCYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8877869-B2 Method for selecting organic sulfur compound for golf ball, method for producing golf ball, and golf ball SRI SPORTS LIMITED (JP) 2014-11-04 US disclosed
US-20120135823-A1 METHOD FOR SELECTING ORGANIC SULFUR COMPOUND FOR GOLF BALL, METHOD FOR PRODUCING GOLF BALL, AND GOLF BALL SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2012-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120135823-A1 METHOD FOR SELECTING ORGANIC SULFUR COMPOUND FOR GOLF BALL, METHOD FOR PRODUCING GOLF BALL, AND GOLF BALL GIGYF2, FKBP4, GSS MEN1 3444/4885KMT2A 4145/4885THRB 3927/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.