SCHEMBL8510774

SCHEMBL8510774

O=S(=O)(O)c1ccccc1-c1[c]cccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TTR P02766 2/20 0.38
PGAM1 P18669 1/20 0.37
MYC P01106 1/20 0.36
SNCA P37840 2/20 0.36
CHAT P28329 1/20 0.36
FABP4 P15090 1/20 0.35
CCNA2 P20248 1/20 0.35
CDK2 P24941 1/20 0.35
MAPK14 Q16539 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
TSHR P16473 1/20 0.34
NR4A1 P22736 1/20 0.34
CYP1A2 P05177 2/20 0.33
NFKB1 P19838 2/20 0.33
KDM4A O75164 1/20 0.33
USP2 O75604 1/20 0.33
NSD2 O96028 1/20 0.33
ALPL P05186 1/20 0.33
PLCG1 P19174 1/20 0.33
TNNI3 P19429 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5030908 0.81 HSD11B1 (0.40) SMN1; SMN2ALDH1A1MEN1KMT2A
SCHEMBL8510448 0.81 NPC1 (0.30) SMN1; SMN2TSHRALDH1A1MAPK1HSD17B10
SCHEMBL3435329 0.79 HTR6 (0.46) TSHRALDH1A1KMT2A
SCHEMBL7195701 0.78 MYC (0.38) TTRPGAM1MYCSNCACHAT
SCHEMBL7179095 0.77 FEN1 (0.41) TSHRCYP1A2L3MBTL1ALDH1A1
SCHEMBL458284 0.77 SMN1; SMN2 (0.48) TTRPGAM1MYCSNCACHAT
SCHEMBL11306716 0.77 MEN1 (0.31) ALPLL3MBTL1STAT3MEN1KMT2A
SCHEMBL10542755 0.76 TSHR (0.33) SMN1; SMN2TSHR
SCHEMBL8509470 0.76
SCHEMBL28837581 0.75 SMN1; SMN2 (0.46) TTRPGAM1MYCSNCACHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5980590-A HIGH COLOR YIELD; FOR DYEING OR PRINTING OF CELLULOSIC FIBERS, WOOL, AND POLYAMIDE FIBERS DYSTAR TEXILFARBEN GMBH & CO. DEUTSCHLAND KG (DE) 1999-11-09 US disclosed
EP-0093306-B1 METHODS FOR THE PREPARATION OF AZO COMPOUNDS, AND AZO COMPOUNDS BAYER AG (DE) 1986-09-24 EP disclosed
EP-0093306-A1 Methods for the preparation of azo compounds, and azo compounds BAYER AG (DE) 1983-11-09 EP disclosed