Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL287733 | 0.87 | S1PR1 (0.38) | HTR2CABCB1PSMB5PTGS2HTR1A | |
| SCHEMBL28000628 | 0.82 | ABCB1 (0.47) | ABCB1PTGS2HTR1AFEN1 | |
| SCHEMBL22275 | 0.81 | ABCB1 (0.47) | HTR2CABCB1HTR1AFEN1HPGD | |
| SCHEMBL19182356 | 0.81 | HTR1A (0.35) | ABCB1PSMB5PTGS2HTR1AHTR7 | |
| SCHEMBL28153847 | 0.81 | PSMB5 (0.34) | ABCB1PSMB5PTGS2 | |
| SCHEMBL28152698 | 0.79 | PTGS2 (0.39) | ABCB1PTGS2HPGD | |
| SCHEMBL28152691 | 0.78 | CHRNB2 (0.38) | HTR2CABCB1FEN1 | |
| SCHEMBL68108 | 0.78 | PTGS2 (0.39) | PSMB5PTGS2FEN1 | |
| SCHEMBL3499337 | 0.78 | ALOX5AP (0.37) | HTR2CABCB1HTR1AFEN1 | |
| SCHEMBL28152695 | 0.77 | ABCB1 (0.43) | ABCB1PTGS2HTR1AHTR7FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2139838-B1 | A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL]-2-NAPHTOIC ACID | GRINDEKS JSC (LV) | 2012-03-28 | — | — | EP | claimed |
| EP-2139838-A2 | A PROCESS FOR THE PREPARATION OF 6-Ý3-(1-ADAMANTYL)-4-METHOXYPHENYL-2-NAPHTOIC ACID | Grindeks, a joint stock company (LV) | 2010-01-06 | — | — | EP | claimed |
| WO-2008080992-A2 | A PROCESS FOR THE PREPARATION OF 6-[3-(1-ADAMANTYL)-4-METHOXYPHENYL-2-NAPHTOIC ACID | KALVINSH IVARS (LV) | 2008-07-10 | — | — | WO | claimed |