Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.34 |
| ▸ | FEN1 | P39748 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28152698 | 0.91 | PTGS2 (0.39) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL27711469 | 0.83 | PTGS2 (0.48) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL4476579 | 0.81 | CHRNB2 (0.57) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL28816105 | 0.81 | CHRNB2 (0.57) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL28483547 | 0.81 | PTGS2 (0.42) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL287733 | 0.80 | S1PR1 (0.38) | PTGS2PSMB5 | |
| SCHEMBL28000625 | 0.80 | ABCB1 (0.42) | PTGS2CHRNB2CHRNA4PTPN5FEN1 | |
| SCHEMBL27820231 | 0.80 | PTGS2 (0.37) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| Phosphine SCHEMBL2085260 | 0.80 | CHRNB2 (0.59) | PTGS2CHRNB2CHRNA4POLBCASP3 | |
| SCHEMBL27995875 | 0.80 | CHRNB2 (0.58) | PTGS2CHRNB2CHRNA4POLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 290 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106573946-A | Complex compounds | 庄信万丰股份有限公司 | 2017-04-19 | — | — | CN | claimed |
| CN-101253144-A | Process for preparing aniline | SYNGENTA PARTICIPATIONS AG (CH) | 2008-08-27 | — | — | CN | claimed |
| CN-115260057-B | Improved method for preparing functionalized cis-trans dicyanoethylene compound through desulfurization of 2, 5-dinitrothiophene | 中国科学院大学 | 2023-07-25 | — | — | CN | disclosed |
| US-10870715-B2 | Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method | MITSUI CHEMICALS, INC. (JP) | 2020-12-22 | — | — | US | disclosed |
| EP-3159333-B1 | BENZO-FUSED THIOPHENE OR FURAN COMPOUNDS COMPRISING A TRIPHENYLENE GROUP | UNIVERSAL DISPLAY CORP (US) | 2020-04-22 | — | — | EP | disclosed |
| US-10374171-B2 | Organic electroluminescent materials and devices | UNIVERSAL DISPLAY CORPORATION (US) | 2019-08-06 | — | — | US | disclosed |
| EP-3312200-B1 | SOLID POLYALUMINOXANE COMPOSITION, OLEFIN POLYMERIZATION CATALYST, OLEFIN POLYMER PRODUCTION METHOD AND SOLID POLYALUMINOXANE COMPOSITION PRODUCTION METHOD | MITSUI CHEMICALS INC (JP) | 2019-06-19 | — | — | EP | disclosed |
| EP-2305672-B1 | SULFUR-CONTAINING HETEROCYCLIC DERIVATIVE HAVING ß-SECRETASE-INHIBITING ACTIVITY | SHIONOGI & CO (JP) | 2019-03-27 | — | — | EP | disclosed |
| US-10150823-B2 | Solid polyaluminoxane composition, olefin polymerization catalyst, olefin polymer production method and solid polyaluminoxane composition production method | MITSUI CHEMICALS, INC. (JP) | 2018-12-11 | — | — | US | disclosed |
| EP-3121187-B1 | METALLOCENE COMPLEX AND METHOD FOR MANUFACTURING OLEFIN POLYMER | JAPAN POLYPROPYLENE CORP (JP) | 2018-10-10 | — | — | EP | disclosed |
| US-20180261778-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2018-09-13 | — | — | US | disclosed |
| WO-2003091225-A1 | SUBSTITUTED PYRAZINE DERIVATIVES | PHARMACIA & UPJOHN COMPANY (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2003084972-A1 | RHODIUM COMPLEXES AND IRIDIUM COMPLEXES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
| WO-2003048225-A2 | PROCESS FOR PRODUCING ARYL-ARYL COUPLED COMPOUNDS | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2003-06-12 | — | — | WO | disclosed |
| US-20030018035-A1 | Substituted arylpyrazines | NEUROGEN CORPORATION | 2003-01-23 | — | — | US | disclosed |
| EP-1255740-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2002-11-13 | — | — | EP | disclosed |
| WO-2002081488-A1 | RHODIUM AND IRIDIUM COMPLEXES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2002-10-17 | — | — | WO | disclosed |
| US-20020058844-A1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1199303-A1 | Process for producing retinol and intermediate compounds for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-04-24 | — | — | EP | disclosed |
| WO-2001060806-A2 | SUBSTITUTED ARYLPYRAZINES | NEUROGEN CORPORATION (US) | 2001-08-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180261778-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | TPR, EED, TEAD2 | PTGS2 1723/4885CHRNB2 2793/4885CHRNA4 2353/4885 |
| US-20020058844-A1 | Process for producing retinol and intermediate compounds for producing the same | ADH4, ADH1B, ADH7 | PTGS2 3119/4885CHRNB2 3249/4885CHRNA4 2596/4885 |
| US-10374171-B2 | Organic electroluminescent materials and devices | TPR, EED, TEAD2 | PTGS2 1723/4885CHRNB2 2793/4885CHRNA4 2353/4885 |
| US-20030018035-A1 | Substituted arylpyrazines | CRHR1, CRHR2, CRH | PTGS2 1819/4885CHRNB2 245/4885CHRNA4 207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.