Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.37 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.36 |
| ▸ | TKT | P29401 | 1/20 | 0.36 |
| ▸ | MOGAT2 | Q3SYC2 | 1/20 | 0.36 |
| ▸ | CSF1R | P07333 | 2/20 | 0.36 |
| ▸ | KIT | P10721 | 2/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
| ▸ | FLT1 | P17948 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155905 | 0.80 | PIK3CA (0.41) | KCNH2TRPV4 | |
| SCHEMBL3851699 | 0.77 | DAO (0.50) | DAOCYP3A4CYP3A5TKTKCNH2 | |
| SCHEMBL9766728 | 0.76 | TRPV3 (0.40) | KCNH2 | |
| SCHEMBL9607440 | 0.75 | DAO (0.40) | DAOCYP2C9CYP3A4CYP2C19GRM2 | |
| SCHEMBL9607481 | 0.75 | PDE2A (0.53) | DAOCYP2C9CYP3A4CYP2C19CYP3A5 | |
| SCHEMBL9607470 | 0.74 | DAO (0.43) | DAOCYP2C9CYP3A4CYP2C19GRM2 | |
| SCHEMBL8514972 | 0.73 | SLC6A4 (0.46) | DAOSLC6A4SLC6A3 | |
| SCHEMBL9158414 | 0.72 | PIK3CA (0.40) | KCNH2PPARD | |
| SCHEMBL12224352 | 0.71 | NFKB1 (0.50) | DAOCYP3A4TKTNPC1TP53 | |
| SCHEMBL9156900 | 0.71 | RARB (0.40) | MOGAT2KCNH2PPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |