Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.39 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.39 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.39 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.39 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | PPARD | Q03181 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TRPV3 | Q8NET8 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8511689 | 0.75 | DAO (0.42) | DAOCYP3A4CYP3A5KCNQ3KCNQ2 | |
| SCHEMBL9607481 | 0.75 | PDE2A (0.53) | DAOCYP3A4CYP3A5KCNQ3KCNQ2 | |
| SCHEMBL9607399 | 0.74 | BCL2L1 (0.41) | DAOMRGPRX4 | |
| SCHEMBL3737879 | 0.74 | CPS1 (0.41) | DAOCYP3A4MRGPRX4 | |
| SCHEMBL9607470 | 0.74 | DAO (0.43) | DAOCYP3A4CYP3A5GRM2CYP2C9 | |
| SCHEMBL5322039 | 0.73 | TRPV4 (0.44) | TRPV3KCNH2MRGPRX4 | |
| SCHEMBL2075208 | 0.70 | GAA (0.54) | CYP2C9CYP2C19 | |
| SCHEMBL3732581 | 0.68 | DAO (0.41) | DAOCYP3A4CYP3A5KCNQ3KCNQ2 | |
| SCHEMBL4853173 | 0.68 | TRPV1 (0.49) | KCNQ3KCNQ2KCNQ4KCNQ5CYP2C9 | |
| SCHEMBL91511 | 0.68 | TRPV4 (0.52) | DAOCYP3A4CYP3A5KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |