Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.37 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PI4KA | P42356 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18003308 | 0.79 | SRD5A2 (0.44) | DAOMAOB | |
| SCHEMBL18003520 | 0.78 | PIK3CA (0.50) | TRPV4PIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL18003284 | 0.78 | MRGPRX4 (0.43) | DAOCSF1RTRPV4KDM1AMAOA | |
| SCHEMBL14661987 | 0.75 | SCN9A (0.47) | — | |
| SCHEMBL8511689 | 0.74 | DAO (0.42) | DAOCYP2C9CSF1RTRPV4CYP3A4 | |
| SCHEMBL9607440 | 0.74 | DAO (0.40) | DAOCYP2C9CYP3A4GRM2CYP3A5 | |
| SCHEMBL25949721 | 0.74 | CALM1 (0.44) | — | |
| SCHEMBL18003466 | 0.73 | DAO (0.41) | DAOCYP2C9CSF1RTRPV4CYP3A4 | |
| SCHEMBL9607166 | 0.72 | DAO (0.42) | DAOSLC6A4 | |
| SCHEMBL28061649 | 0.72 | MET (0.44) | DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069856-A1 | ANTIMALARIAL COMPOUNDS | LIVERPOOL SCHOOL OF TROPICAL MEDICINE (GB) | 2012-05-31 | — | — | WO | disclosed |