SCHEMBL8512366

SCHEMBL8512366

CCCC(=O)OC(=O)c1c(I)c(NC(C)=O)c(I)c(NC(C)=O)c1I

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.49
ALDH1A1 P00352 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
MAPK1 P28482 1/20 0.33
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.30
HPGD P15428 1/20 0.30
RECQL P46063 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27647105 0.87 LMNA (0.47) LMNAALDH1A1SMN1; SMN2MAPK1KDM4E
SCHEMBL8773948 0.80 LMNA (0.58) LMNAALDH1A1SMN1; SMN2KDM4ETSHR
SCHEMBL9016363 0.79 LMNA (0.46) LMNAALDH1A1SMN1; SMN2MAPK1KDM4E
SCHEMBL332859 0.78 LMNA (0.54) LMNAALDH1A1SMN1; SMN2MAPK1KDM4E
SCHEMBL10031588 0.75 LMNA (0.59) LMNAALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL8814469 0.74 LMNA (0.50) LMNAALDH1A1SMN1; SMN2MAPK1KDM4E
SCHEMBL9102086 0.74 LMNA (0.58) LMNAALDH1A1SMN1; SMN2KDM4EHPGD
SCHEMBL9414491 0.73 LMNA (0.43) LMNAALDH1A1SMN1; SMN2KDM4ETSHR
SCHEMBL9016334 0.73 LMNA (0.53) LMNAALDH1A1SMN1; SMN2KDM4ETSHR
SCHEMBL8230945 0.73 LMNA (0.53) LMNAALDH1A1SMN1; SMN2KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1870979-A Process for production of essentially solvent-free small particles BAXTER INT (US) 2006-11-29 CN disclosed
US-5862999-A GRINDING DRUG (E.G., DANAZOL) WITH NONCONTAMINATING, RIGID GRINDING MEDIUM NANO SYSTEMS L.L.C. (US) 1999-01-26 US disclosed